The number of presumed monkeypox cases detected in New York City has surpassed 600 amid an ongoing shortage of vaccines to combat the outbreak, officials said Monday.  

As of Monday, 618 people in the five boroughs had tested positive for presumed monkeypox, up from 461 on Friday, the city’s Department of Health and Mental Hygiene said. 

The department noted that there are “likely more cases that have not been diagnosed,” and said most of those who had tested positive had “not been hospitalized and have recovered on their own.” 

The latest update came days after the city opened up 9,200 vaccine appointment slots as part of its effort to meet what the city’s health commissioner, Dr. Ashwin Vasan, described as “incredibly high” demand for the vaccine. 

The supply the city has received from the federal government so far has been “extremely limited,” Vasan said in an interview with NY1’s Pat Kiernan on Thursday. 

All 9,200 appointment slots filled up within seven minutes on Friday, the health department said in a press release. Thousands of those doses were administered at three pop-up mass vaccination sites on Sunday. 

Due to limited supply, the 9,200 slots were reserved for “gay, bisexual, or other men who have had sex with men and transgender, gender non-conforming, or gender non-binary persons ages 18 and older who have had multiple or anonymous sex partners in the last 14 days,” the department said. 

As of July 13 — when the city was reporting 336 cases — 95.5% of those testing positive identified as men, 2.1% identified as transgender, gender nonconforming or non-binary and 2.4% were cases the city identified as “unknown,” health department data shows.

Nearly 60% of the 336 people testing positive identified as members of the city’s LGBTQ communities, while 0.6% identified as straight and 39.6% were still listed as “unknown” due to “pending case investigations,” according to the data. 

Manhattan reported 203, or about 60%, of the 336 cases, Brooklyn reported 60, Queens reported 38, the Bronx reported 34 and Staten Island reported one case.

Both the federal government and the city have faced criticism for their handling of the outbreak so far — the former for the shortage of vaccine supply, and the latter for a vaccine rollout plagued by technical issues. 

The city’s health department on Friday said it was “working to get vaccine[s] to New Yorkers as soon as possible.” 

Statewide, New York is set to receive more than 32,000 monkeypox vaccine doses this week. 

“In addition to the appointments that went online [Friday], we will continue to receive appointments for people referred by community partner organizations serving highest-risk patients,” the health department said. “We will advise New Yorkers when more appointments can be made.” 

New Yorkers can sign up for monkeypox-related alerts by texting MONKEYPOX to 692692, the department noted.