Three people have been charged in connection with the homicides of two men who investigators say were drugged, robbed and killed in separate incidents after visiting Manhattan bars last year, prosecutors say.

Jayqwan Hamilton, 35, and Robert Demaio, 34, have been indicted on charges including second-degree murder, first-degree robbery, identify theft and grand larceny for their alleged roles in the deaths of John Umberger and Julio Ramirez, the Manhattan district attorney’s office said Tuesday.

Jacob Barroso, 29, has also been indicted on charges including second-degree murder and first-degree robbery in connection with Ramirez’ death, the DA’s office said.  

Ramirez, a 25-year-old social worker, and Umberger, a 33-year-old political consultant from Washington D.C., were targeted after frequenting bars in Manhattan’s Hell Kitchen in April and May 2022, respectively, police and prosecutors said.

Linda Clary, the mother of John Umberger, said in November that her son’s bank accounts were drained of about $23,000 after he was last seen leaving Q NYC on Eighth Avenue.

Umberger was later found dead in an Upper East Side apartment. A medical examiner’s report, released last month, deemed Umber’s death a drug-facilitated homicide. It found multiple drugs, including fentanyl, in his system.

Six weeks prior to Umberger’s death, Ramirez was last seen alive leaving The Ritz Bar and Lounge in Hell’s Kitchen. 

Police found him on the Lower East Side unresponsive in the back of a taxi. He died, and thousands of dollars were also taken from his accounts.

Earlier this month, police said the two homicides were being investigated as part of a larger citywide robbery pattern, which included 17 incidents in total between Sept. 19, 2021, and Aug. 28, 2022.

Two additional suspects, Andre Butts, 27, and Shane Hoskins, 30, were arrested in March in connection with the series of robberies, police and prosecutors said.

They have been indicted on charges including first-degree robbery, fourth-degree conspiracy, identity theft and grand larceny, according to prosecutors.

“I cannot imagine how painful it is for the families of Mr. Ramirez and Mr. Umberger. My thoughts continue to be with them,” Manhattan District Attorney Alvin Bragg said at a news conference Tuesday. “It is my sincere hope that today will bring some solace to the fact that our investigations have now led to these charges.”

Attorney information for the five men was not immediately available Tuesday.